Non-PEG-Derived Polyethers as Solid Supports. 1. Synthesis, Swelling Studies, and Functionalization
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چکیده
منابع مشابه
Biopolymer Synthesis on Solid Supports
The concept of solid phase synthesis began as a new approach to the preparation of peptides, but has been extended to the synthesis of polynucleotides, polysaccharides, polyamides and a variety of other classes of compounds. The solid support simplifies and accelerates the synthetic process, aids the separation of reagents and by-products, and reduces problems of insolubility of intermediates. ...
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Planar supports represent a unique opportunity in designing novel approaches to solid-phase synthesis of peptides and small organic molecules. Published work includes assembly on cellulose paper sheets, cotton strips, or membranes, as well as ultrahigh-density synthesis on glass supports. Planar carriers allow for the synthesis to be performed without any reaction vessels (inclusion volume chem...
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We describe the preparation of several types of porous silicon (pSi) microparticles as supports for the solid-phase synthesis of oligonucleotides. The first of these supports facilitates oligonucleotide release from the nanostructured support during the oligonucleotide deprotection step, while the second type of support is able to withstand the cleavage and deprotection of the oligonucleotides ...
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ژورنال
عنوان ژورنال: Journal of Combinatorial Chemistry
سال: 2003
ISSN: 1520-4766,1520-4774
DOI: 10.1021/cc0200686